详细介绍
总览
光遗传学（optogenetics）——结合遗传工程与光来操纵个别神经细胞的活性。这方法有助于发展一系列脑相关失调的新疗法。
Teleopto无线光遗传学刺激器由耦合了高精度LED光源的无线光导纤维,远程控制器,接收器及相关配件组成。
高精度LED光源的光导纤维是高亮度的LED灯源和光导纤维耦合而成,实现输出功率达到mW级。应用这个技术可以获取高精度的LED光源。所需光源颜色不同,选择不同的光导纤维。
无线光遗传学刺激器突破了传统的有线刺激,解放了动物,使其不再受到连接线带来的束缚,动物可以自由活动,使其处于更自然的状态下,有利于实验获取精准的数据。
产品特征
实验动物自由活动,不受束缚
通过红外遥控操作
适用于大鼠和小鼠
接收器体积微小且轻便
兼容性强
光源精度高,稳定
多种光源颜色可选
参考文献
Excitatory connections between the prelimbic and infralimbic medial prefrontal cortex show a role for the prelimbic cortex in fear extinction.
Roger Marek, Li Xu, Robert K.P.Sullivan, Pankaj Sah
Nature Neuroscience (2018) 21(5):654-658.DOI: 10.1038
Top-down cortical input during NREM sleep consolidates perceptual memory.
Miyamoto D, Hirai D, Fung CCA, Inutsuka A, Odagawa M, Suzuki T, Boehringer R, Adaikkan C, Matsubara C, Matsuki N, Fukai T, McHugh TJ, Yamanaka A, Murayama M
Science (2016) 352(6291): 1315-8.DOI: 10.1126
Htr2a-Expressing Cells in the Central Amygdala Control the Hierarchy between Innate and Learned Fear.
Isosaka T, Matsuo T, Yamaguchi T, Funabiki K, Nakanishi S, Kobayakawa R, Kobayakawa K
Cell (2015) 163(5):1153-64
A Top-Down Cortical Circuit for Accurate Sensory Perception.
Manita S, Suzuki T, Homma C, Matsumoto T, Odagawara M, Yamada K, Ota K, Matsubara C, Inutsuka A, Sato M, Ohkura M, Yamanaka A, Yanagawa Y, Nakai J, Hayashi Y, Larkum ME, Murayama M
Neuron (2015) 86:1304-16
The lateral parabrachial nucleus is actively involved in the acquisition of fear memory in mice.
Sato M, Ito M, Nagase M, Sugimura YK, Takahashi Y, Watabe AM, Kato F
Molecular Brain (2015) 8:22
